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Therapeutics
Delivery of 100%, 40%, and blow-by humidity did not differ for change in croup scores in children with moderate croup

https://doi.org/10.1136/ebm.11.5.142

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    Scolnik D, Coates AL, Stephens D, et al. Controlled delivery of high vs low humidity vs mist therapy for croup in emergency departments: a randomized controlled trial. JAMA 2006;295:1274–80.
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 Q In children presenting to the emergency department (ED) with moderate croup, what is the relative effectiveness of 100% humidity with optimally sized water particles, 40% humidity, and humidity delivered by the blow-by technique?

    Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Respirology ★★★★★★☆ Emergency medicine ★★★★★☆☆

    METHODS

    Embedded ImageDesign:

    randomised controlled trial.

    Embedded ImageAllocation:

    {concealed}*.†

    Embedded ImageBlinding:

    blinded (healthcare providers, data collectors, and {data analysts}*).†

    Embedded ImageFollow up period:

    30 and 60 minutes.

    Embedded ImageSetting:

    ED at the Hospital for Sick Children, Toronto, Ontario, Canada.

    Embedded ImagePatients:

    140 children 3 months to 10 years of age (mean age 25 mo, 69% boys) who presented with croup lasting ⩽1 week and had Westley croup scores ⩾2 out of 17 after a 30 minute rest period. Exclusion criteria were need for immediate nebulised epinephrine or intubation, potential alternative cause of stridor, history of intubation, chronic systemic or pulmonary disease other than asthma, use of …

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    Footnotes

    • ↵* Information provided by author.

    • ↵† See glossary.

    • For correspondence: Dr D Scolnik, Hospital for Sick Children, Toronto, Ontario, Canada. dennis.scolnik{at}sickkids.ca

    • Source of funding: Physicians’ Services Incorporated Foundation of Ontario.

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      BMJ Evidence-Based Medicine 2006; 11 159a-159a Published Online First: 29 Sep 2006. doi: 10.1136/ebm.11.5.159a