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- hot flashes
- plant preparations
- vasomotor system
- cimicifuga
- estrogen replacement therapy
- phytotherapy
- soy foods
Q Do herbal supplements relieve vasomotor symptoms of menopause in women?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ IM/Ambulatory care ★★★★★★☆
METHODS
Design:
randomised placebo controlled trial (Herbal Alternatives for Menopause Trial [HALT]).
Allocation:
concealed.*
Blinding:
blinded (clinicians, participants, {data collectors, and outcome assessors}†).*
Follow up period:
12 months.
Setting:
Washington State, USA.
Patients:
351 women 45–55 years of age (mean age 52 y, 93% white) who were in menopausal transition or postmenopausal with ⩾2 vasomotor symptoms per day for 2 weeks (⩾6 moderate to severe symptoms). Exclusion criteria included contraindications to hormone therapy (HT), use of HT or oral contraceptives in the past 3 months, use of herbal medicines in the past month, bilateral oophorectomy, or history of breast cancer.
Intervention:
black cohosh (Actaea racemosa or Cimicifuga racemosa), 160 …