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Dr C Crowther
Correspondence to: Dr C Crowther, University of Adelaide, Adelaide, South Australia, Australia; firstname.lastname@example.org
In women at risk of preterm birth, what is the effectiveness and safety of multiple doses of antenatal corticosteroids (ACSs) compared with a single dose for preventing neonatal respiratory disease?
Studies comparing repeat dose(s) of ACSs with placebo or no treatment for preventing neonatal morbidity in women still at risk of preterm delivery ⩾7 days after a first dose were selected. Outcomes were respiratory distress syndrome, severe lung disease, serious infant morbidity, birthweight, perinatal mortality, and maternal morbidity.
Cochrane Pregnancy and Childbirth Group’s trials register (February 2007); Cochrane Central Register of Controlled Trials, Medline, EMBASE/Excerpta Medica, and Current Contents (to November 2006); reference lists; and abstracts of major congresses were searched for randomised controlled trials (RCTs). Experts …
Source of funding: Australian Department of Health and Aging.