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  • Review: restricted dietary salt intake can reduce blood pressure but does not reduce death or cardiovascular morbidity

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Therapeutics
Review: restricted dietary salt intake can reduce blood pressure but does not reduce death or cardiovascular morbidity

https://doi.org/10.1136/ebm.8.5.139

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    (2003) Cochrane Database Syst Rev 1, CD003656. Hooper L, Bartlett C, Davey Smith G, et al.. Reduced dietary salt for prevention of cardiovascular disease.. ;. (. ). :. (latest version 26 Feb 2003).

    
 
 QUESTION: In people with normal and elevated blood pressure (BP), does a reduction in dietary salt decrease blood pressure, death, or cardiovascular events?

    Data sources

    Studies were identified by searching the Cochrane Library, Medline, and EMBASE/Excerpta Medica; reviewing bibliographies or relevant studies; and contacting authors.

    Study selection

    2 reviewers independently selected randomised controlled trials (RCTs) that compared interventions designed to reduce salt intake with placebo or no active intervention in adults (≥16 y) with normal or high BP. Institutionalised, acutely ill, or pregnant people were excluded.

    Data extraction

    2 reviewers independently assessed the quality of RCTs (randomisation method, allocation concealment, blinding, and losses to follow up) and extracted data on patient characteristics, interventions and type of controls, …

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    Footnotes

    • Source of funding: North West Research and Development Training Fellowship.

    • For correspondence: Ms L Hooper, University Dental Hospital of Manchester, Manchester, UK. lee.hooper{at}man.ac.uk