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Since publication of the Women's Health Initiative Study, the potential benefits of non-pharmacological therapies for menopause-related symptoms have gained increased interest among midlife women, clinicians and researchers.1 Interventions requiring behavioural change have yielded mixed outcomes, owing to small sample sizes, a variety of outcome measures, lack of control groups and limited follow-up.2–4
To assess the effects of exercise, yoga and ω-3 therapy on menopause-specific quality of life, MS-FLASH investigators conducted a multisite factorial design (3×2), randomised controlled trial in which women were randomised to 12 weeks of exercise, yoga or usual activity and simultaneously randomised to receive ω-3 supplements …
Competing interests None.
Provenance and peer review Commissioned; internally peer reviewed.