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Epidural injections with local anaesthetics have been performed since 1901, and with corticosteroids since 1952. The use of epidural injections in clinical practice continues to increase.1–4 Despite multiple randomised controlled trials, systematic reviews, and clinical guidelines, there are conflicting and discordant recommendations regarding their use,3 ,4 with some high profile publications reporting a lack of efficacy,5 including the systematic review and meta-analysis discussed here.
Chou and colleagues performed a systematic review of randomised controlled trials of …
Competing interests LM has provided limited consulting services to Semnur Pharmaceuticals, Incorporated, which is developing non-particulate steroids.
Provenance and peer review Commissioned; internally peer reviewed.