Table of contents

Therapeutics

• Randomised controlled trial: Cardiac resynchronisation therapy is efficacious in patients with mild heart failure symptoms (24 March, 2011)

  Nawaf S Al-Majed, Justin A Ezekowitz
• Randomised controlled trial: Oral rivaroxaban for acute DVT, or long term for VTE, is as effective as enoxaparin followed by a vitamin K antagonist for preventing recurrence, with no increase in bleeding complications (3 April, 2011)

  David J Rosenberg, Jack Ansell
• Randomised controlled trial:

  Lactobacillus rhamnosus GG reduces frequency and severity of abdominal pain compared with placebo in children with irritable bowel syndrome

  (3 April, 2011)

  Markus A Rose
• Systematic review with meta-analysis: NSAID use associated with increased cardiovascular risk and death, but naproxen appears to be the least harmful (3 April, 2011)

  Brian Bluhm, Lee A Green
• Systematic review: α-blockers and antibiotics, alone or in combination, improve symptoms in men with chronic prostatitis/chronic pelvic pain syndrome (25 April, 2011)

  Gianpaolo Perletti, Vittorio Magri
• Randomised controlled trial: Addition of omeprazole to dual antiplatelet therapy with clopidogrel plus aspirin lowers the risk of upper gastrointestinal bleeding (10 May, 2011)

  Jolanta M Siller-Matula, Georg Delle-Karth
• Randomised controlled trial: Oral antiretroviral pre-exposure prophylaxis reduces the risk of HIV acquisition among men who have sex with men (10 May, 2011)

  Marie-Claude Boily, Benoît R Mâsse, Dobromir Dimitrov
• Randomised controlled trial: CBT stress management reduces recurrent CAD events after myocardial infarction (24 June, 2011)

  Peter A Shapiro
• Randomised controlled trial: Initial treatment of hypertension with aliskiren and amlodipine combination gives 6.5 mm Hg greater reduction in systolic BP than does either monotherapy (18 August, 2011)

  John M Flack, Samar A Nasser, Phillip D Levy
• Randomised controlled trial: Amoxicillin-clavulanate improves symptoms, reduces treatment failure in select children with acute otitis media and increases risk of diarrhoea (7 July, 2011)

  Andrea Marmor, Thomas B Newman
• Randomised controlled trial: PREDIMED trial: Mediterranean diet may reduce the risk of type 2 diabetes (8 May, 2011)

  Michel de Lorgeril
• Systematic review with meta-analysis: Vitamin D supplementation of deficient children may improve bone mineral density (10 May, 2011)

  Leticia Manning Ryan
• Randomised controlled trial: Training birth attendants in rural Zambia in neonatal resuscitation, and the use of amoxicillin coupled with facilitated referral, reduces neonatal mortality (10 May, 2011)

  David R Marsh, Stephen N Wall
• Randomised controlled trial: Two weeks of rifaximin relieves global symptoms and bloating in people with IBS without constipation (24 April, 2011)

  Brennan Spiegel
• Randomised controlled trial: The quadrivalent HPV vaccine is effective prophylaxis against HPV-related external genital lesions in young men (10 May, 2011)

  Basil Donovan, Andrew E Grulich
• Randomised controlled trial: Escitalopram reduced hot flashes in non-depressed perimenopausal and postmenopausal women (10 May, 2011)

  Claudio N Soares